Clinical Genome Resource (ClinGen)

ClinGen is a National Institutes of Health (NIH)-funded resource dedicated to building an authoritative central resource that defines the clinical relevance of genes and variants for use in precision medicine and research. ACMG coordinates the three expert panels within the Inborn Errors of Metabolism clinical domain, as well as the Somatic work group.  ACMG staff are aiding in the development of training modules on variant curation, as well as asking locus specific databases (with variant data for different genes related to the expert panels in progress) to submit their data to the ClinGen curation efforts.  The ACMG meetings coordinator plans all the ClinGen face-to-face meetings (e.g., steering committee, expert panel, and work group meetings).

ACMG is a sub-contractor under #1U01HG007437-01.

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National Coordinating Center for the Regional Genetics Networks (NCC)

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The mission of the seven Regional Genetics Networks (RGNs), the National Coordinating Center (NCC), and the National Genetics , and the National Genetics Education and Family Support Center (Family Center) was to improve access to genetic services for underserved populations.

This project was supported by the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services (HHS) under Cooperative Agreement #UH9MC30770 from 6/2020-5/2024 for $800,000 per award year.

Funding for this program concluded in September 2024, marking the program’s completion. However, the website remains available as a public resource.

Newborn Screening Translational Research Network (NBSTRN)

The mission of the Newborn Screening Translational Research Network (NBSTRN) was to facilitate newborn screening research to discover novel technologies, treatments, and interventions through the development of resources, tools, and expertise. The NBSTRN was a key component of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Hunter Kelly Newborn Screening Research Program. The American College of Medical Genetics and Genomics (ACMG) operated the NBSTRN through a contract from NICHD.

This project was funded in whole with Federal funds from the NICHD, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN275201800005C.

Funding for this program concluded in March 2024, marking the program’s completion.

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