Genetic testing is becoming an integral part of clinical medicine as genomic information increasingly informs patient care across the lifespan for both healthy individuals and those with disease. The value of genetic testing in the care of patients who may have inherited conditions, such as cancer1 and cardiac disease,2 is well established. Carrier screening is recommended for all individuals who are pregnant or planning a pregnancy, and prenatal cell-free DNA screening has become a standard genetic screening option during pregnancy.